We reviewed the species composition and abundance, fauna,geographical distribution and conservation situation of reptiles occurred in Hubei by studying literature published in the recent 20 years. A total of 78 species of reptile was listed under 44 genera,12 families and 2 orders. Most of them are distributed in southwest (57 species,73.1%),northwest (47 species,60.3%) and southeast (43 species,55.1%) parts of Hubei. A total of 62 (79.5%) of them are oriental realm species,8 (10.3%) palearctic realm species and 8 (10.3%) widespread species, respectively. Within the oriental realm species, 36 (58.1%) of them are originated in the central and south area of China, 15 (24.2%) species are originated in the central area of China, and 11 (17.7%) species are originated in the southeast area of China. A total of 25 species (32.1%) are listed in the "China Species Red List", and 16 species (20.5%) are list as protected species in Hubei. The reptiles in Hubei Province are non-random distribution and the fauna of reptile is dominated by oriental realm species and most of them are listed as protected species.