The successive observation was conducted to study the artificial fertilized embryos and fry of Megalobrama hoffmanni from June to July in 2007. The post-embryonic development were divided into 12 stages based on the external morphology, internal morphogenesis; each stage were described and photographed. The characteristics of M. hoffmanni is very obvious: The body is somewhere transparent, with few pigments on the head; Beside the otic capsule there are some pigments developing into pigment flower; The shape of pigments in the fore part of belly likes a Calabash Gourd, which fades gradually after the formation of ventral fin; The length of caudal is 31% to 46% of the total length; After one chamber air bladder stage, total muscle nodes are about 43 pairs, including more than 19 pairs muscle nodes in the caudal. After developing and growing for 24 days, with formation of all fins, the fry gets the same characters as the adult M. hoffmanni.