In the present study, the hybrids were artificially bred among blunt snout bream Megalobrama amblycephala and three Megalobrama species including M. skolkovii, M. terminalis and M. pellegrini using reciprocal crosses methods. The morphologic characteristics of intermuscular bones in hybrids as well as inbreds of four species were investigated and compared, totally 10 groups. Among the individuals from these 10 groups (Table 1), the number of intermuscular bones was ranged from 96 to 134 with the average number of 119 (Table 2). There were no significant differences among the 10 groups and M. pellegrini inbreds had the minimum intermuscular bones with the mean value of 114. The length of intermuscular bones of the same fish had the linear relationship with the body weight and body length of fish individuals in these 10 groups (Table 3 and 4, Fig. 1-4). The length of intermuscular bones in the different part had significant difference (P < 0.05), while the intermuscular bone in the epiaxial muscle of dorsal part were significantly longer than the other three parts including (P < 0.05) hypaxial muscle and epiaxial muscle of tail part, hypaxial muscle of dorsal part (Table 5). The number of intermuscular bones in hypaxial muscle of dorsal part was significantly less than other parts (P < 0.05) and there was no significant difference between hypaxial muscle and epiaxial muscle of tail part (P > 0.05) (Table 6). There were 6 kinds of intermuscular bones in the hybrids, including “1” type, “卜” type, “y” type, one-end-multifork type, twen'zwo-end-multifork type, and “（” type, with more complex shapes in the front part of body (Table 7). All the results indicated that the hybridization among the Megalobrama species had no distinct changes for the intermuscular bones.