MicroRNA (miRNA), a class of non-coding RNA (about 20-25 nt), was found in eukaryotes and has function of regulation and control. Many research results have confirmed that miRNAs play an important role in many life processes in eukaryotes, involving the individual development, metabolism, cell growth and apoptosis, etc. At present, there are relatively few miRNA data in goat. This article summarizes the regulation of miRNAs in skin and hair follicle development, muscle growth and development, lactation and reproduction of goat. This review will provide theoretical basis and research insight for using miRNAs to regulate and improve the quality of wool and cashmere, the growth and reproductive performance in goat.