Under the global resource and environmental crisis, macro-zoology in the level of species and ecology has become an important subject for the sustainable development. Based on visualization analysis of two agencies, Key Laboratory of Zoological Systematics and Evolution, Chinese Academy of Sciences and Natural History Museum in London, in the field of zoology research in 2009-2013, we revealed the status quo, hotspot, differences and future development trends of them. We found that two agencies had very similar research direction in macro zoology that was classification, system evolution and biodiversity. Key Laboratory of Zoological Systematics and Evolution’s author clustering focused in insect research, but Natural History Museum in London’s research had a wider diversity and regions span. At present the Key Laboratory of Zoological Systematics and Evolution’s main hotspot and the research frontiers was still classic taxonomic study of China's new species. Research focus of the Natural History Museum in London had already turned to the discovery and trace of new species in the developing countries such as China and India. Species diversity and phylogenetic studies on the basis of classical taxonomy was Natural History Museum in London’s research forefront on macro zoology.