Using the morphological and histological technology to study the development of digestive system of Qinglong grouper(Epinephelus coioides ♀×E. lanceolatus ♂), and described its development processes of digestive organs and structure of organization. Studies showed that the digestive system development of Qinglong grouper could be divided into three stages: the endogenous vegetative stage (0－3 DAH), the larvae completely relied on the yolk sac, and didn’t have the feeding and digestion. The mixed vegetative stage (4－5 DAH), the mouth and anus opened, the digestive tract ran through. The exotrophic stage (after 6 DAH), the yolk sac had been completely absorbed. The structure and function of the digestive system of Qinglong grouper at 25 DAH developed gradually. In conclusion,development of the digestive system of Qinglong grouper were in accord with the growth,morphology development and perfection of functions during the early development.