Crustacean’s life history composed of molting, which was closely related to the crustacean growth, development, reproduction. Comparing with other creatures, Crustaceans grew discontinuously by molting: the complete shedding of the hardened exoskeleton and the formation of a new one, and the body width and weight to achieve a leapfrog growth in a relatively short period of time. Variability in growth was manifested as more or less frequent molting, depending on intrinsic and extrinsic factors. Intrinsic factors that affected aquatic crustaceans molting include molting hormone, moltinginhibiting hormone, ecdysteroid receptor, retinoid X receptor and gonad development. Extrinsic factors that affected molting include temperature, light, salinity, food supply, Ca2+ and pollution. In this review, we summarized the principal factors which affect the growth of aquatic crustaceans molting, focusing on influence of the intrinsie mechanism, and provided an overview of research progresses in the molting of aquatic crustaceans at home and abroad. Finally, we discussed the future direction of development of aquatic crustacean molting and growth.