首页 > 过刊浏览>2012年第47卷第6期 >136-143
PDF HTML阅读 XML下载 导出引用 引用提醒
甲状腺激素在两栖动物变态过程中的作用
作者:
基金项目:

中央高校基本科研业务费专项资金项目(No.GK261001)


The Role of Thyroid Hormone in the Amphibian Metamorphosis
Author:
  • 摘要
    • | |
  • 访问统计
    • |
  • 参考文献 [48]
    • |
  • 相似文献
    • |
  • 引证文献
    • | |
  • 文章评论
    摘要:

    两栖动物的幼体变态是研究甲状腺激素调节组织和器官重构的理想模式。本文主要综述了近年来两栖动物甲状腺激素合成过程中3种脱碘酶D1、D2和D3的特点及其生物学功能;甲状腺激素受体的蛋白结构、类型和机能;以及甲状腺激素对两栖动物幼体变态过程中各个类型组织和器官重构的调节;甲状腺激素、甲状腺激素受体和脱碘酶的互作,并展望了今后的研究方向。

    Abstract:

    Amphibian metamorphosis is an ideal model system to understand the action of the thyroid hormone (TH) on the remolding of tissue and organ. Firstly, the characteristics and functions of three types of deiodinases are reviewed. Emphasis is laid on the structure, the types and functions of thyroid hormone receptors. The remolding of tissue and organ in amphibian metamorphosis regulated by TH is described. Meanwhile, interactions among TH, deiodinase and thyroid hormone receptors in amphibian metamorphosis are discussed. Finally, future perspectives for amphibian metamorphosis studies are proposed.

    参考文献
    [1] Macchia P E. Recent advances in understanding the molecular basis of primary congenital hypothyroidism. Molecular Medicine Today, 2000, 6(1): 36-42.
    [2] Manley N R, Capecchi M R. Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Developmental Biology, 1998, 195(1): 1-15.
    [3] DeVito M, Biegel L, Brouwer A, et al. Screening methods for thyroid hormone disruptors. Environmental Health Perspectives, 1999, 107(5): 407-415.
    [4] Ahmed O M, El-Gareib A W, El-Bakry A M, et al. Thyroid hormones states and brain development interactions. International Journal of Developmental Neuroscience, 2008, 26(2): 147-209.
    [5] Bassett J H, Boyde A, Howell P G, et al. Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts. Proceedings of the National Academy of Sciences of the United States of America, 2010, 107(16): 7604-7609.
    [6] Galton V A. The roles of the iodothyronine deiodinases in mammalian development. Thyroid, 2005, 15 (8): 823-834.
    [7] Gereben B, Zavacki A M, Ribich S, et al. Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocrine Reviews, 2008, 29(7): 898-938.
    [8] St Germain D L, Galton V A, Hernandez A. Minireview: defining the roles of the iodothyronine deiodinases: current concepts and challenges. Endocrinology, 2009, 150(3): 1097-1107.
    [9] Bianco A C, Kim B W. Deiodinases: implications of the local control of thyroid hormone action. Journal of Clinical Investigation, 2006, 116(10): 2571-2579.
    [10] Brown D D, Cai L Q. Amphibian metamorphosis. Developmental Biology, 2007, 306(1): 20-33.
    [11] Das B, Matsuda H, Fujimoto K, et al. Molecular and genetic studies suggest that thyroid hormone receptor is both necessary and sufficient to mediate the developmental effects of thyroid hormone. General and Comparative Endocrinology, 2010, 168(2): 174-180.
    [12] Zhang J S, Lazar M A. The mechanism of action of thyroid hormones. Annual Review of Physiology, 2000, 62: 439-466.
    [13] Yen P M. Physiological and molecular basis of thyroid hormone action. Physiological Reviews, 2001, 81 (3): 1097-1142.
    [14] Feng X, Jiang Y, Meltzer P, et al. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Molecular Endocrinology, 2000, 14(7): 947-955.
    [15] Flores-Morales A, Gullberg H, Fernandez L, et al. Patterns of liver gene expression governed by TRbeta. Molecular Endocrinology, 2002, 16(6): 1257-1268.
    [16] Furlow J D, Neff E S. A developmental switch induced by thyroid hormone: Xenopus laevis metamorphosis. Trends in Endocrinology and Metabolism, 2006, 17(2): 40-47.
    [17] Tata J R. Amphibian metamorphosis as a model for studying the developmental actions of thyroid hormone. Biochimie, 1999, 81(4): 359-366.
    [18] Schreiber A M, Mukhi S, Brown D D. Cell-cell interactions during remodeling of the intestine at metamorphosis in Xenopus laevis. Developmental Biology, 2009, 331(1): 89-98.
    [19] Tata J R, Kawahara A, Baker B S. Prolactin inhibits both thyroid hormone-induced morphogenesis and cell death in cultured amphibian larval tissues. Developmental Biology, 1991, 146(1): 72-80.
    [20] 崔之兰. 北方狭口蛙Kaloula borealis(Barbour)蝌蚪尾在变态期退化过程中的组织学观察. 北京大学学报: 自然科学版, 1966, 12(1): 78-90.
    [21] Oofusa K, Yoshizato K. Biochemical and immunological characterization of collagenase in tissues of metamorphosing bullfrog tadpoles. Development, Growth & Differentiation, 1991, 33(4): 329-339.
    [22] Berry D L, Schwartzman R A, Brown D D. The expression pattern of thyroid hormone response genes in the tadpole tail identifies multiple resorption programs. Developmental Biology, 1998, 203(1): 12-23.
    [23] Das B, Cai L Q, Carter M G, et al. Gene expression changes at metamorphosis induced by thyroid hormone in Xenopus laevis tadpoles. Developmental Biology, 2006, 291(2): 342-355.
    [24] Smulson M E, Simbulan-Rosenthal C M, Boulares A H, et al. Roles of poly (ADP-ribosyl) ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1. Advances in Enzyme Regulation, 2000, 40(1): 183-215.
    [25] Sirakov M, Plateroti M. The thyroid hormones and their nuclear receptors in the gut: from developmental biology to cancer. Biochimica et Biophysica Acta, 2011, 1812(8): 938-946.
    [26] McAvoy J W, Dixon K E. Cell specialization in the small intestinal epithelium of adult Xenopus laevis: structural aspects. Journal of Anatomy, 1978, 125(1): 155-169.
    [27] Heimeier R A, Das B, Buchholz D R, et al. Studies on Xenopus laevis intestine reveal biological pathways underlying vertebrate gut adaptation from embryo to adult. Genome Biology, 2010, 11(5): R55.
    [28] Schreiber A M, Cai L, Brown D D. Remodeling of the intestine during metamorphosis of Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(10): 3720-3725.
    [29] Shi Y B, Brown D D. The earliest changes in gene expression in tadpole intestine induced by thyroid hormone. Journal of Biological Chemistry, 1993, 268(27): 20312-20317.
    [30] Shi Y B, Hayes W P. Thyroid hormone-dependent regulation of the intestinal fatty acid-binding protein gene during amphibian metamorphosis. Developmental Biology, 1994, 161(1): 48-58.
    [31] Ishizuya-Oka A, Shimozawa A. Inductive action of epithelium on differentiation of intestinal connective tissue of Xenopus laevis tadpoles during metamorphosis in vitro. Cell and Tissue Research, 1994, 277(3): 427-436.
    [32] Mukhi S, Horb M E, Brown D D. Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis. Developmental Biology, 2009, 328(2): 384-391.
    [33] Mukhi S, Mao J, Brown D D. Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105(26): 8962-8967.
    [34] Paik W K, Cohen P P. Biochemical studies on amphibian metamorphosis. I. The effect of thyroxine on protein synthesis in the tadpole. Journal of General Physiology, 1960, 43(4): 683-696.
    [35] Atkinson B G, Warkman A S, Chen Y. Thyroid hormone induces a reprogramming of gene expression in the liver of premetamorphic Rana catesbeiana tadpoles. Wound Repair and Regeneration, 1998, 6(4): 323-337.
    [36] Mukhi S, Cai L Q, Brown D D. Gene switching at Xenopus laevis metamorphosis. Developmental Biology, 2010, 338(2): 117-126.
    [37] Patel J, Landers K, Li H, et al. Thyroid hormones and fetal neurological development. Journal of Endocrinology, 2011, 209(1): 1-8.
    [38] Haddow J E. Hypothyroidism: detecting and treating early symptoms as the body's energy rheostat is slowly turned down. Journal of Medical Screening, 2010, 17(4): 163.
    [39] Huggins P, Johnson C K, Schoergendorfer A, et al. Identification of differentially expressed thyroid hormone responsive genes from the brain of the Mexican Axolotl (Ambystoma mexicanum). Comparative Biochemistry and Physiology C:Toxicology & Pharmacology, 2012, 155(1): 128-135.
    [40] Du Pasquier L, Robert J, Courtet M, et al. B-cell development in the amphibian Xenopus. Immunological Reviews, 2000, 175(1): 201-213.
    [41] Cai L Q, Brown D D. Expression of type II iodothyronine deiodinase marks the time that a tissue responds to thyroid hormone-induced metamorphosis in Xenopus laevis. Developmental Biology, 2004, 266(1): 87-95.
    [42] Huang H, Cai L Q, Remo B F, et al. Timing of metamorphosis and the onset of the negative feedback loop between the thyroid gland and the pituitary is controlled by type II iodothyronine deiodinase in Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America, 2001, 98(3): 7348-7353.
    [43] Yen P M, Feng X, Flamant F, et al. Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. Embo Reports, 2003, 4(6): 581-587.
    [44] Eliceiri B P, Brown D D. Quantitation of endogenous thyroid hormone receptors alpha and beta during embryogenesis and metamorphosis in Xenopus laevis. Journal of Biological Chemistry, 1994, 269(39): 24459-24465.
    [45] Galay-Burgos M, Power D M, Llewellyn L, et al. Thyroid hormone receptor expression during metamorphosis of Atlantic halibut (Hippoglossus hippoglossus). Molecular and Cellular Endocrinology, 2008, 281(1/2): 56-63.
    [46] Ng L, Lyubarsky A, Nikonov S S, et al. Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. Journal of Neuroscience, 2010, 30(9): 3347-3357.
    [47] Marsh-Armstrong N, Huang H, Remo B F, et al. Asymmetric growth and development of the Xenopus laevis retina during metamorphosis is controlled by type III deiodinase. Neuron, 1999, 24(4): 871-878.
    [48] Morvan-Dubois G, Sebillot A, Kuiper G G J M, et al. Deiodinase activity is present in Xenopus laevis during early embryogenesis. Endocrinology, 2006, 147 (10): 4941-4949.
    相似文献
    引证文献
    引证文献 [1]
    网友评论
    网友评论
    分享到微博
    发 布
引用本文

陈婧,吴民耀,王宏元.2012.甲状腺激素在两栖动物变态过程中的作用.动物学杂志,47(6):136-143.

复制
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2012-04-26
  • 最后修改日期:2012-09-11
  • 在线发布日期: 2012-12-19
  • 邮政编码：100101  电话：010-64807162
  • 通讯地址：北京 朝阳区 北辰西路1号院5号 中国科学院动物研究所
  • E-MAIL
  • journal@ioz.ac.cn

版权所有 ©《动物学杂志》编辑部 技术支持：北京勤云科技发展有限公司 京ICP备05064604号-1