IIn order to understand the nutritional components and quality in muscle of fish Takifugu flavidus, Takifugu obscurus and their hybrid F1 generation,we took 9 tails them to measure the contents of crude protein,crude fat, moisture, ash and amino acids in the muscle as well as the growth rate. compared to their parents, the hybrid individuals grew significantly faster than their parents; their weight of hybrid indiwiduals increased by 148%-177%,showing a marked hybrid vigour . The muscle of crossbreed F1 had lower crude fat content thanthat of its parents, while the moisture and crude protein content was similar (P＞0.05.Total of 16 amino acids were detected in the muscle samples of hybrid F1 and the content showed significant difference except(P＜0.05)except Try and Cys,The total amino acids in T. obscurus (♀) ×T. flavidus (♂) were higher than that in T. flavidus and lower than that in T. obscurus ,while the T. flavidus (♀) × T. obscurus (♂) had highest content of total amino acids. There was no significant difference between crossbreed F1 and T. obscurus in total essential amino acids (P＞0.05),while the difference between crossbreed F1 and T. flavidus was significant (P＜0.05).The composition of total tasty amino acids in the muscle of thecrossbreed F1 of T. flavidus(♀) ×T. obscures(♂) was 26.68% which was significantly higher than that in T. flavidus(22.88%) and T. obscures(25.20%),while the total tasty amino acids in crossbreed F1 of T. obscurus (♀) ×T. flavidus (♂)(23.30%) was higher thanthat in T. flavidus and lower than in T. obscures.Our results showed that the muscle in the crossbreed F1, especially the T. flavidus(♀) ×T. obscures(♂) crossbreed, had higher essential amino acids and tasty amino acids, and it minght be a new promising candidate for aquaculture.