This study was carried out to determine the effect of starvation on body appearance,muscle composition and blood biochemistry of the Coilia nasus which were cultivated with the indoor condition in 20 days. The experimental groups were sampled on 0 day (control), 2 days, 5 days, 10 days and 20 days. The results showed: there was a significant(P<0.05) trend to decline for hepatosomatic index and andviserosomatic index in the 2_nd day, while the effect of obese relative and body weight were not different(P＞0.05)in the 20_th day. There was a significant (P< 0.05) trend to decline for the crude fat in the body muscle of the Coilia nasus for 5.99% on the 5_th day, while the trend of body contents of crude protein declined in the 15_th day. During the period of starvation ,there was a significant(P<0.05) trend to increase for contents of moisture in the 10th day while content of crude ash does not change significantly(P＞0.05). With the starvation time extending, serum total protein, globulin, cortisol and cholesterin present a trend of increasing,then decreasing while serum triglycerides and glucose fell sharply and maintain a certain level which triglycerides decrease significantly in the 2_nd day (P<0.05) and blood glucose decrease significantly in the 2_nd day (P<0.05).The experiment illustrated that the Coilia nasus body appearance had changed,and with the prolongatin of starvation, the muscle fat was decompose to exploit first, the muscle protein then to be used, at the same time, the body biochemical of the Coilia nasus was changed to be fit for the starvation condition．