| 杜宗君,段亚佼,黄小丽,汪开毓,段靖,邓永强,耿毅,陈德芳.2017.荧光假单胞菌感染大鲵的病理损伤.动物学杂志,52(3):537-542. |
| 荧光假单胞菌感染大鲵的病理损伤 |
| Pathological Lesions of Chinese Giant Salamander (Andrias davidianus) Infected by Pseudomonas fluorescents |
| 投稿时间：2016-08-05 修订日期：2017-04-06 |
| DOI：10.13859/j.cjz.201703021 |
| 中文关键词: 大鲵 荧光假单胞菌 病理损伤 |
| 英文关键词:Chinese Giant Salamander, Andrias davidianus Pseudomonas putida Pathological lesions |
| 基金项目:四川省十三五育种攻关项目（2016NYZ0047） |
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| 中文摘要: |
| 通过对感染荧光假单胞菌（Pseudomonas fluorescents）发病的大鲵（Andrias davidianus）主要器官进行病理剖解和病理组织学观察，以明确大鲵感染荧光假单胞菌引起的病理学损伤特点。结果表明，大鲵感染荧光假单胞菌后，主要表现为腹部极度膨胀、腹水和严重胃肠道反应，严重者可见将胃呕吐至口腔；组织器官具有典型的病理变化，其主要靶器官为肾、肝、肠道、皮肤和肌肉。分别引起坏死性肾小球肾炎、肝炎。此外，还可引起轻微肠炎及皮炎。可在肾小管管腔内、肝细胞坏死灶内、肠道固有层内及皮肤肌肉中发现数量极多的杆状细菌。 |
| 英文摘要: |
| The pathological anatomy and hitopathology of diseased Chinese Giant Salamander (Andrias davidianus) infected by Pseudomonas fluorescents were examined. The results showed that the diseased fish had extremely swelling abdomen with severe vomiting (Fig. 1a). Some stomachs even reached mouth due to vomitting (Fig. 1b). The serious lesions occurred in the kidney, liver, intestine, skin and muscle, causing necrotic glomerular nephritis and hepatitis, and mild enteritis and dermatitis. Renal tubular epithelial cells showed severe edema and big vacuoles in the cytoplasm (Fig. 2c). Urinary cylinder in kidney tubules (Fig. 2a), renal interstitial capillary congestion (Fig. 2b) and eosinophils infiltration in renal interstitial (Fig. 2d) could also be observed. A large number of bacteria appeared in the tubular lumen (Fig. 2e). Hepatic cells showed severe edema (Fig. 2f) and enlargement with a large number of bacilli (Fig. 2g﹣h). Lysis also appeared in the liver. Lamina propria showed severe edema (Fig. 2i) infiltrated with bacilli (Fig. 2j). Capillary congestion and inflammatory cell infiltration were observed in epidermis (Fig. 2k). Also, a large number bacilli existed in the muscle tissue (Fig. 2l). |
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